Indian Oil has filed a patent for an improved process to produce xylitol from pure xylose. The method involves using a specific yeast strain, incubation at varying temperatures, and continuous addition of glucose and inducer for enhanced xylitol production in a short time. GlobalData’s report on Indian Oil gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Indian Oil, Bioethanol production GMOs was a key innovation area identified from patents. Indian Oil's grant share as of January 2024 was 60%. Grant share is based on the ratio of number of grants to total number of patents.
Improved process for high titer xylitol production from xylose
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A recent patent application (Publication Number: US20230407348A1) discloses an improved process for high titer xylitol production from pure xylose. The process involves inoculating a thermotolerant and inhibitor tolerant yeast strain, such as Saccharomyces cerevisiae DBT-IOC S24, into a culture medium containing pure sugars, yeast extract, nutrient broth, and inducers. The yeast strain is incubated at specific temperatures and agitation levels, with continuous addition of glucose and inducers in pulse feed intervals. The process results in the production of xylitol from the medium, with a xylitol yield of 10.9% in 72 hours of fermentation.
Furthermore, the process includes specific details such as the combination ratio of glucose and xylose in the pure sugars, the concentration of yeast strain inoculation, the selection of inducers like 5-Hydroxymethylfurfural (HMF) and furfural, and the feeding rates of glucose and furfural in the medium. The process is carried out in a fed-batch mode, with adjustments in the concentrations of xylose and glucose to optimize xylitol production. Overall, this patented process offers a systematic and efficient method for producing high titer xylitol from pure xylose, showcasing the potential for improved xylitol production in industrial settings.
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